A Featured Story from MIT Technology Review, by Ken Garber. Not news really, it was published on December 1, 2002.
Of interest especially the heralding of how Science has just changed:
when it was found in 2001 that “tiny double-stranded RNA fragments quickly, easily, and specifically turned off genes in human cells, a role researchers had never before seen RNA play”
“…Most of the audience was just sitting there saying to themselves, Science has just changed”
and this opens avenues for ‘RNA Prescriptions:
“The Holy Grail is to develop all this into drugs,” says Zamore. “To be able to give you a small interfering RNA that would shut off expression of your high-cholesterol gene. That would lower the level of hepatitis C infecting your liver. Or maybe, I think in perhaps the biggest pie-in-the-sky application, that would hone in on a gene specific to tumor cells and kill the tumor.”
http://www.technologyreview.com/featuredstory/401727/prescription-rna/
And in 2014 it seems that they have found the right delivery route:
http://www.technologyreview.com/featuredstory/530631/gene-silencing-drugs-finally-show-promise/?utm_campaign=newsletters