… to remember to explore further:

“So much of this ‘evidence’ is for drug treatment, especially comparing one drug against another. We now have enough research evidence that shows that many of the ‘things’ doctors advise (drug) treatment for, are but markers of an underlying problem. Sadly, these are mostly for the most common of problems – risk markers, not factors, for heart disease and cancer ie the inter-related metabolic syndrome-degenerative disease continuum. Many of the equivocal (and it seems sometimes fraudulent3) studies and meta-analyses of hypotensive, anti-diabetic , lipid-normalising, fat losing drugs are ‘treating’ markers, and, as would be expected are not very effective at improving health or even longevity.”

http://www.bmj.com/content/348/bmj.g3725/rr/761537

A Rapid Response by Anne-Thea McGill
commenting on the paper by Trisha Greenhalgh: Evidence based medicine: a movement in crisis?